these Conclusions take about 2 pages so I need you to rewrite them
� Pedometer measurements can be used to track daily activity easily during COPD exacerbations that do not require hospital admission. We have shown that exacerbations reduce physical activity with patients recovering within a 3 to 4 day period post exacerbation.
� Frequent exacerbations also hasten a decline in activity over time and potentially this patient group would benefit from greater encouragement to continue exercising.
� Our results also show that daily activity is a major drive for patients reporting exacerbation events and seeking additional therapy. Thus, non-hospitalised COPD exacerbations are key events that not only cause symptomatic deterioration but also impair the patients� activity.
� There are a number of important implications to this work. Patients with COPD should be encouraged to increase physical activity as pulmonary rehabilitation reduces breathlessness, improves quality of life and exercise tolerance. Inactivity is greatest during cold weather and perhaps pulmonary rehabilitation programmes should be targeted in the winter to limit this inactivity.
� Activity is reduced at weekends and patient education should encourage patients to maintain activity on these days. This study provides evidence of an effect on the daily activity of COPD patients of atmospheric pollution at higher levels and public health schemes to reduce levels of atmospheric pollution should be further encouraged.
� Our findings suggest that a greater rise in systemic inflammation at exacerbation is associated with a larger reduction in exercise capacity which is associated with increases in symptoms of depression and fatigue.
� Decreases in exercise capacity and physical activity at exacerbation are greater in those with more severe disease and those with a history of frequent exacerbations. It is possible that prior pulmonary rehabilitation may protect against loss of exercise capacity and physical activity at exacerbation.
� Daily step counts measured by a pedometer averaged over one month correlated well with objective tests of physical capacity, time outdoors, daily peak flow, disease severity, and quadriceps muscle strength; they also related to systemic inflammation levels. Pedometry is a simple, cheap method for quantifying daily physical activity in COPD patients over a long period of time.
� Pedometry may be a useful way prospectively to monitor and quantify physical daily activity during COPD exacerbations in a large observational cohort.